This study investigates the adoption challenges of Farmonaut’s Management Information System (MIS), a satellite-based smart agriculture solution, within the Bo‘ka and Chinoz districts of Uzbekistan. Using the Technology-Organization-Environment (TOE) framework, the research analyzes how infrastructural limitations, institutional dynamics, and environmental constraints influence the implementation of digital agricultural technologies. Employing a qualitative case study approach grounded in secondary data, the findings reveal key technological barriers such as limited internet access, low digital literacy, and lack of system localization. Organizational challenges include inadequate managerial support, weak training programs, and poor inter-agency coordination. Environmentally, the efficacy of MIS tools is hindered by climate variability, land degradation, and underdeveloped irrigation infrastructure. Despite these limitations, the study identifies areas of potential, particularly when supported by localized training, policy incentives, and public-private partnerships. The results offer policy-relevant insights into how smart farming technologies can be tailored to fit the specific socio-economic and environmental contexts of developing countries.